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NOW: SAMe 200 mg. Description: Nervous System Support Stabilized SAMe, Capsule Form No Enteric Coating Needed Supports Joint Health Non-GMO A Dietary Supplement Vegetarian/Vegan Amino Acids Family Owned Since 1968 GMP Quality AssuredSAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health. SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, contributes to the maintenance of healthy cell membrane function, and influences cartilage metabolism. Suggested Use: Take 1 capsule 2 to 4 times daily, preferably on an empty stomach.Refrigeration recommended after opening. Other Ingredients: Hypromellose (cellulose capsule), microcrystalline cellulose, silicon dioxide and stearic acid (vegetable source).Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens. Warnings Caution: For adults only. Individuals with bipolar depression, anxiety disorders or taking antidepressant medications should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.Natural color variation may occur in this product.