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Tylenol Complete Could, Cough & Flu - Extra Strength - 24s* is a fast‑acting multipurpose relief remedy designed to ease cold, cough, flu, and congestion symptoms; each yellow daytime caplet combines 500 mg of extra‑strength acetaminophen, 15 mg of dextromethorphan HBr, 100 mg of guaifenesin and 30 mg of pseudoephedrine to reduce pain, suppress cough, loosen mucus and relieve nasal congestion, while the blue nighttime caplets—also with 500 mg of acetaminophen and 30 mg of pseudoephedrine plus 25 mg of diphenhydramine—add antihistamine support to help with runny nose, sneezing and nighttime symptom relief.