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Guaifenesin 600 mg extended-release tablets are an expectorant designed to relieve chest congestion associated with common colds, infections, or irritants. Guaifenesin works by loosening and thinning mucus in the airways, making it easier to expel through coughing and promoting more comfortable breathing. Formulations like Mucinex offer a bi-layer tablet that provides both immediate and extended release of the medication, providing relief for up to 12 hours. It is recommended for adults and children over 12 years old, with a typical dosage of one tablet every 12 hours, not exceeding two tablets in 24 hours. It's important to follow the product instructions and consult a healthcare professional if symptoms persist or worsen. Additionally, staying well-hydrated can enhance the medication's effectiveness.