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Description Caprosyn™ monofilament synthetic absorbable sutures are prepared from Polyglytone™ 6211 synthetic polyester which is composed of glycolide, caprolactone, trimethylene carbonate, and lactide. Indications Caprosyn™ synthetic absorbable sutures are indicated for use in general soft tissue approximation and/or ligation, but not for use in ardiovascular or neurological surgery, microsurgery, or ophthalmic surgery. Actions Caprosyn™ synthetic absorbable sutures elicit a minimal acute inflammatory reaction in tissues, which is followed by gradual encapsulation of the suture by fibrous connective tissue. Progressive loss of tensile strength and eventual absorption of Caprosyn™ synthetic absorbable sutures occurs by means of hydrolysis. Tensile Strength Caprosyn™ suture retains a minimum of 50 to 60% USP and EP knot strength at 5 days post implantation, and a minimum of 20 - 30% of USP and EP knot strength at 10 days post implantation. All of the original tensile strength is essentially lost by 21 days post implantation. Sterilization Ethylene oxide. Absorption Absorption begins as a loss of tensile strength followed by a loss of mass. Absorption of Caprosyn™ synthetic absorbable suture is essentially complete by 56 days. Packaging Caprosyn™ synthetic absorbable sutures are available undyed (natural) or dyed with D&C Violet No. 2 in USP sizes 1 (4 metric) through 6-0 (0.7 Metric). The sutures are supplied sterile, in pre-cut lengths or ligating reels, nonneedled or affixed to various needle types. The sutures are available in box quantities of one, two and three dozen. Please refer to the individual package IFUs for complete instructions, indications, contraindications, warnings and precautions.