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Option+: Arthritis Pain Relief Extended Release Tablets 650 mg. Option+ Arthritis Pain Relief Acetaminophen Extended Release Tablets USP 650 mg provides up to 8 hours of relief from minor muscular aches and pain commonly caused by arthritis as well as relief from menstrual cramps, headaches, and aches & pains due to flu/fever. Features: Extended release. Up to 8 hours of relief.