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Preparation H® Multi-Symptom Hemorrhoid Treatment Ointment with Bio-Dyne, 25g Tube. Multi‑symptom ointment delivers targeted relief by gently shrinking swollen hemorrhoidal tissue and soothing pain, itching, burning, irritation, and discomfort. Enriched with Bio‑Dyne (a yeast extract long favored in the Canadian formulation), phenylephrine HCl as a vasoconstrictor, and protectants like petrolatum and mineral oil, it forms a gentle barrier that eases bowel movements and soothes inflamed areas. Designed for both internal and external use, it provides prompt, soothing comfort when applied up to four times daily as directed.